科研进展

【论文题目】Preparation, characterization, antioxidant, and antifungal activity of phenyl/indolyl-acyl chitooligosaccharides（苯基/吲哚酰基壳寡糖的制备、表征及其抗氧化与抗真菌活性）

【作者】Fang Wen, Yao Liu, Hehe Yang, Xu Yan, YanDong Zhang, Zhimei Zhong*（温舫，刘瑶，杨贺贺，闫旭，张燕东，钟志梅*）

【Abstract】In this study, carboxylic acids compounds were grafted onto chitooligosaccharides to prepare seven phenyl/indolyl-acyl chitooligosaccharides derivatives. The structures of the derivatives were characterized by IR spectroscopy, ¹³CNMR and elemental analysis. Meanwhile, antioxidant activities in vitro of the novel derivatives were analyzed. Compared to COS and carboxylic acid, the derivatives showed higher scavenging capacity for superoxide anion and DPPH radicals, with scavenging rates of 59.39% and 94.86%, respectively. The hydroxyl radical scavenging ability of the derivatives was only 18.89%. The antifungal activities of chitooligosaccharide derivatives against Diaporthe batatas and Phytophthora capsici were studied by the growth rate method. Compared with chitooligosaccharide itself, derivatives were inhibited by 97.77% and 100%. The above results showed that chitooligosaccharide derivatives have good biocompatibility and can be used in food, agriculture and medicine.

【Keywords】Chitooligosaccharide; Heterocyclic compounds; Antioxidant activity; Antifungal activity

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